Diagnosis and treatment of hepatic angiomyolipoma: an analysis of 81 patients / 中华肝胆外科杂志

ABSTRACT

Objective To study the clinical manifestations,imaging and pathological features of,and to analyse our experience in diagnosing and treatment of,hepatic angiomyolipoma.Methods The clinical manifestations,imaging features,pathological morphology and immunohistochemical characteristics of hepatic angiomyolipoma from 81 patients were analyzed retrospectively.Results Twenty patients had clinical symptoms.A preoperative imaging diagnosis was made in 20 patients.Radical liver resection was performed in 61 patients,liver biopsy in 2 patients,and radiofrequency ablation after liver biopsy in 18 patients.All tumor cells expressed the markers of melanoma cells (HMB 45,mart-1) and smooth muscle cells.Recurrence of tumor was found in one patient after operation (1.2％,1/81).No patients died on follow-up.Conclusions The imaging manifestations of hepatic angiomyolipoma were varied,and the diagnosis depended on pathological findings and immunohistochemistry staining.The treatment strategy should be selected according to tumor size,location and clinical symptoms.Patients should be followed-up closely after surgery because of the malignant potential of hepatic angiomyolipoma.