Herpes virus and Alzheimer's disease: the debate and new evidence / 中华神经科杂志

ABSTRACT

Alzheimer's disease is a chronic progressive neurodegeneration disease,currently the pathogenesis of which is not fully elucidated and no disease-modifying therapies are available.The amyloid-beta cascade hypothesis is still predominant in the field.Although has been proposed for decades,the herpes virus hypothesis remains controversial due to lack of solid evidence.New evidence supporting the hypothesis is emerging while debates remain,which would be the focus of this paper.