Research progress of urinary dysfunction in patients with Parkinson's disease / 中华神经科杂志

ABSTRACT

Parkinson's disease is a neurodegenerative disease characterized by abnormal α-synuclein deposition.The main clinical manifestation is dyskinesia.With the deepening of research,the non-motor symptoms of Parkinson's disease are gradually recognized,and the urinary symptoms such as daytime frequency and urinary urgency affect the quality of patients' life.Urinary symptoms of Parkinson's disease also reflect the lesions in the brain,such as the D1 dopaminergic bladder inhibitory pathway of the prefrontal nigrostriatal tract.Therefore,its early diagnosis and treatment is essential.This article reviews the progress of urinary dysfunction in Parkinson's disease.