One case of hereditary angioneurotic laryngeal edema / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 1222-1222, 2013.
Article
in Zh
| WPRIM
| ID: wpr-747143
Responsible library:
WPRO
ABSTRACT
Hereditary angioneurotic laryngeal edema (HALE) is an autosomal dominant hereditary disease in which there is a decrease or defect in the C1 inhibitor (C1-INH). The pathophysiology of HALE is characterized by recurrent spontaneous episodes of transient edema of the laryngeal mucose and submucosal tissue with remission at irregular. Patients may die because of a life-threatening acute upper airway obstruction caused by laryngeal edema. HALE was diagnosed on the clinical symptoms, family history, and markedly decreased serum C1-INH activity and C1-INH protein.
Full text:
1
Index:
WPRIM
Main subject:
Recurrence
/
Complement C1 Inactivator Proteins
/
Laryngeal Edema
/
Diagnosis
/
Complement C1 Inhibitor Protein
/
Angioedemas, Hereditary
/
Metabolism
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Zh
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2013
Type:
Article