Present research on the status and the prospect of insulin-like growth factor-I in head and neck cancer / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 717-720, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-747402
ABSTRACT
Insulin-like growth factor-I (IGF-I) is a multifunctional cell regulating factor, which plays an important role in the normal physiological activities and pathological process, This article reviewed the research status of the molecular structure of IGF- I and its regulatory factors, the molecular biological role of IGF- I in cell proliferation, cell motility, apoptosis, and reviewed the important role of IGF-I in head and neck tumor, as well as put forward the prospects of IGF-I in middle ear cholesteatoma pathogenesis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Insulin-Like Growth Factor I
/
Cell Movement
/
Apoptosis
/
Cell Proliferation
/
Head and Neck Neoplasms
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2012
Type:
Article
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