Expression of MEF2D on nasopharyngeal carcinoma tissues and its influence of prognostic / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 840-847, 2011.
Article
in Zh
| WPRIM
| ID: wpr-748044
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To explore the expression of MEF2D in NPC tissues, study the relationship between the expression and prognostic.@*METHOD@#Specimens from 101 NPC patients who were follow-up visited 1 to 7 years were analyzed for MEF2D by using immunohistochemistry.@*RESULT@#(1) The expression of MEF2D was higher in the higher clinical stage. (2) Density and Grey of MEF2D was negative correlated (|r| = 0.865, P < 0.01). (3) NPC patients' survival rate after therapies was 52.5%, the survival curve of 1th clinical stage was higher than 4th. (4) The survival curves of MEF2D stages were no statistical significance.@*CONCLUSION@#There's statistical significance of the MEF2D expression in clinical stages, but not in survival curve, which indicated that MEF2D concerned with invasion and metastatic of NPC.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Prognosis
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Carcinoma
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Carcinoma, Squamous Cell
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Nasopharyngeal Neoplasms
/
Myogenic Regulatory Factors
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MADS Domain Proteins
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MEF2 Transcription Factors
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Nasopharyngeal Carcinoma
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Lymphatic Metastasis
Type of study:
Prognostic_studies
Limits:
Adult
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Female
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Humans
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Male
Language:
Zh
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2011
Type:
Article