The correlation between ultrastructure of lymphatic capillary and neck lymph node metastasis laryngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 267-272, 2007.
Article
in Zh
| WPRIM
| ID: wpr-748860
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To study the correlation between ultrastructure of lymphatic capillary in pericancerous tissue and neck lymph node metastasis in laryngeal carcinoma.@*METHOD@#Transmission electronic microscope was applied to observe and compare ultrastructure of lymphatic capillary in 8 normal laryngeal epithelial tissue and 12 pericancerous tissue of laryngeal cancer.@*RESULT@#Lymphatic capillary of pericancerous tissue was significantly dilated compared with normal laryngeal tissue. A large amount of endothelial cell junction was open and devoid of basement membrane. Some endothelial cells of lymphatic capillary were destroyed or broken completely.@*CONCLUSION@#Ultrastructure of lymphatic capillary in pericancerous tissue is an important factor of laryngeal cancer metastasis through lymphatic system. This research offers theoretic basis for laryngeal carcinoma metastasis mechanism and prevention.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Carcinoma, Squamous Cell
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Case-Control Studies
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Laryngeal Neoplasms
/
Lymphatic Vessels
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Microscopy, Electron, Transmission
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Laryngeal Mucosa
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Lymph Nodes
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Lymphatic Metastasis
/
Neck
Type of study:
Observational_studies
Limits:
Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2007
Type:
Article