Clinical Application of Near-Infrared Spectroscopy in Neonates
Neonatal Medicine
; : 121-127, 2019.
Article
in En
| WPRIM
| ID: wpr-760590
Responsible library:
WPRO
ABSTRACT
The incidence of cerebral palsy has not decreased despite advances in neonatal care. Preterm infants are at a high risk of cerebral palsy. Moreover, preterm infants might experience permanent neurological sequelae due to injury in the preterm brain. Although the etiology of preterm brain injury is not fully understood, preterm brain injury is strongly associated with abnormal cerebral perfusion and oxygenation. Monitoring systemic blood pressure or arterial oxygen saturation using pulse oximetry is not enough to guarantee proper cerebral perfusion or oxygenation. Early detection of improper cerebral perfusion can prevent irreversible cerebral damage. To decrease brain injury through the early detection of under-perfusion and deoxygenation, other diagnostic modalities are needed. Near-infrared spectroscopy can continuously and noninvasively monitor regional oxygen saturation (rSO₂), which reflects the perfusion and oxygenation status of tissues at bedside. Near-infrared spectroscopy represents a balance between tissue oxygen supply and demand. Cerebral rSO₂ monitoring has been used most frequently in neonatal cardiac surgery to monitor cerebral oxygenation and prevent hypoxic damage or shock. Recently, cerebral, renal, or splanchnic rSO₂ in neonates is frequently monitored. The progression of a disease, brain injury, and death can be prevented by detecting changes in rSO₂ values using near-infrared spectroscopy. In this article, the basic principles, usefulness, and applications of near-infrared spectroscopy in neonates are discussed.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Oxygen
/
Perfusion
/
Shock
/
Splanchnic Circulation
/
Thoracic Surgery
/
Blood Pressure
/
Brain
/
Brain Injuries
/
Infant, Premature
/
Oximetry
Type of study:
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Humans
/
Newborn
Language:
En
Journal:
Neonatal Medicine
Year:
2019
Type:
Article