A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection
Annals of Pediatric Endocrinology & Metabolism
; : 68-70, 2019.
Article
in En
| WPRIM
| ID: wpr-762586
Responsible library:
WPRO
ABSTRACT
Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Polyuria
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Rubella
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Autoantibodies
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Thrombocytopenia
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Urination
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Cataract
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Weight Loss
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Diabetes Mellitus
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Diabetes Mellitus, Type 1
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Ductus Arteriosus, Patent
Limits:
Adolescent
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Humans
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Male
Language:
En
Journal:
Annals of Pediatric Endocrinology & Metabolism
Year:
2019
Type:
Article