The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial
Journal of Menopausal Medicine
; : 29-33, 2018.
Article
in En
| WPRIM
| ID: wpr-765729
Responsible library:
WPRO
ABSTRACT
OBJECTIVES: The present trial aimed to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles. METHODS: In this double blind, randomized and placebo-controlled trial, sixty eligible postmenopausal women were randomly assigned into the fennel and placebo groups. Total blood cholesterol, cholesterol fractions, and triglycerides were tested at the baseline, and after three-month follow-up. RESULTS: There was no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol (LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups. In addition, in both groups, a paired t.test showed no significant difference in all mentioned parameters, except for HDL-C, indicating significant borderline improvement (P = 0.052) in the fennel group. CONCLUSIONS: The fennel group revealed a very slight positive change in LDL-C, triglyceride and HDL-C. Further studies with longer durations, higher doses, and larger sample sizes are recommended to validate the results.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Triglycerides
/
Cholesterol
/
Follow-Up Studies
/
Postmenopause
/
Sample Size
/
Foeniculum
/
Lipoproteins
Type of study:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Journal of Menopausal Medicine
Year:
2018
Type:
Article