Utility of Volume Assessment Using Bioelectrical Impedance Analysis in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective Observational Study / 대한구급학회지
The Korean Journal of Critical Care Medicine
; : 256-264, 2017.
Article
in En
| WPRIM
| ID: wpr-771008
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Fluid overload prior to continuous renal replacement therapy (CRRT) is an important prognostic factor. Thus, precise evaluation of fluid status is necessary to treat such patients. In this study, we investigated whether fluid assessment using bioelectrical impedance analysis (BIA) can predict outcomes in critically ill patients requiring CRRT.METHODS:
A prospective observational study was performed in patients who were admitted to the intensive care unit and who required CRRT. BIA was conducted before CRRT; then, the ratio of extracellular water to total body water (ECW/TBW) was derived to estimate volume status.RESULTS:
A total of 31 patients treated with CRRT were included. There were 18 men (58.1%), and the median age was 67 years (interquartile range, 51 to 78 years). Fourteen patients (45.2%) died within 28 days after CRRT initiation. Patients were divided into 16 with ECW/TBW ≥0.41 and 15 with ECW/TBW <0.41. Survival rate within 28 days was different between the two groups (P = 0.044). Cox regression analysis revealed a relationship between ECW/TBW ≥0.41 and 28-day mortality, but it was not statistically significant (hazard ratio, 3.0; 95% confidence interval, 0.9 to 9.8; P = 0.061). Lastly, the area under the curve of ECW/TBW for 28-day mortality was analyzed. The area under the curve of ECW/TBW was 0.73 (95% confidence interval, 0.54 to 0.92), and this was significant (P = 0.037).CONCLUSIONS:
Fluid status can be assessed using BIA in critically ill patients requiring CRRT, and BIA can predict mortality. Further large trials are needed to confirm the usefulness of BIA in critically ill patients.Key words
Full text:
1
Index:
WPRIM
Main subject:
Body Water
/
Water
/
Survival Rate
/
Prospective Studies
/
Mortality
/
Critical Illness
/
Electric Impedance
/
Renal Replacement Therapy
/
Observational Study
/
Intensive Care Units
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Humans
/
Male
Language:
En
Journal:
The Korean Journal of Critical Care Medicine
Year:
2017
Type:
Article