Korean Medication Algorithm for Bipolar Disorder 2018: Manic Episode / 우울ㆍ조울병
Mood and Emotion
; (2): 13-24, 2018.
Article
in Ko
| WPRIM
| ID: wpr-786876
Responsible library:
WPRO
ABSTRACT
OBJECTIVES: We revised the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) 2014 to provide more timely information for the use of the information by clinicians.METHODS: We performed the survey using a questionnaire for the treatment of manic or hypomanic episode in the participants. There were sixty-one members of the review committee who completed the survey. The executive committee analyzed the results and discussed the final production of the applicable algorithm as considering the scientific evidence.RESULTS: The combination of a mood stabilizer (MS) and an atypical antipsychotic (AAP) was recommended as the treatment of choice (TOC), and a monotherapy with an AAP was the first-line pharmacotherapeutic strategy for the initial treatment of mania, with or without psychotic features. The MS monotherapy was the first-line choice therapy, but only for the non-psychotic mania patients. When the initial treatment failed, the TOC was a combination of a MS and an AAP in mania with or without psychotic features, and a combination of two AAPs was TOC for the psychotic mania, as well. For hypomania, the monotherapy with MS or AAP was the first-line as initial treatment, and the recommended switch to or add an AAP was recommended when the initial strategies failed.CONCLUSION: Compared with the previous version, the experts recommend more intensive interventions earlier when initial treatment failed to respond to a recommended monotherapy.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Bipolar Disorder
/
Advisory Committees
/
Drug Therapy
Type of study:
Prognostic_studies
Limits:
Humans
Language:
Ko
Journal:
Mood and Emotion
Year:
2018
Type:
Article