Treatment of advanced stage cholangiocarcinoma: Systemic therapy may be the starting step for radical surgery
Korean Journal of Clinical Oncology
; (2): 62-65, 2018.
Article
in En
| WPRIM
| ID: wpr-788021
Responsible library:
WPRO
ABSTRACT
Cholangiocarcinoma is the most common biliary malignancy and the second most common hepatic malignancy following hepatocellular carcinoma. It can be classified anatomically as intrahepatic cholangiocarcinoma (iCCA), perihilar CCA, or distal CCA. The treatment of choice for iCCA is surgical resection, but only those with potentially resectable tumors can undergo surgery. The standard regimen for advanced stage iCCA is gemcitabine and cisplatin. We encountered two unusual cases of iCCA patients who were initially diagnosed as unresectable cases and underwent systemic chemotherapy, which showed great response and therefore enabled radical operation. The patients show that even though iCCA is a challenging disease, patients with good response to chemotherapy may have a chance to undergo radical surgery.
Key words
Full text:
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Index:
WPRIM
Main subject:
Cisplatin
/
Cholangiocarcinoma
/
Carcinoma, Hepatocellular
/
Drug Therapy
Limits:
Humans
Language:
En
Journal:
Korean Journal of Clinical Oncology
Year:
2018
Type:
Article