Test result analysis on IgM antibody determination in 367 cases of suspected measles in Changshu City / 上海预防医学

ABSTRACT

[Objective]To analyze the IgM antibody detection results for suspected cases of measles from2013 to 2016 in Changshu City, in order to provide basis for formulation of strategies of prevention and control of measles. [Methods] The serum samples of 367 suspected measles cases were detected for measles IgM by enzyme linked immunosorbent (ELISA) methods. [Results] The serum samples of 246 suspected measles cases were measles IgM positive, the positive rate being 67.03％. The number of cases of measles obviously increased in 2015 and 2016, and the paroxysm of measles tended to occur in the population of low and older ages, showing dipolar pattern. The differences of IgM antibody between different age groups had statistical significance (χ2= 27.03, P < 0.01). Measles broke out mainly from March to August, when there were obvious differences on the positivity of IgM antibody detected at different times after rash occurrence (χ2= 13.62, P < 0.01). [Conclusion] Measles immunization should be enhanced and measles vaccination replenished properly. It is also necessary to raise the rate of measles vaccination among children of suitable age within the jurisdiction. Strengthen monitoring on measles in floating population, enhance vaccine replanting and revaccination of measles in floating population, adult and fertile women and enhance immune level in high incidence population.