Research progress of adverse drug reaction of quinolone antimicrobial agents / 药学实践杂志

ABSTRACT

Quinolones are widely used due to the wide antimicrobial spectrum and strong activity .The common adverse reactions of quinolones include gastrointestinal disturbances ,central nervous system reaction ,skin reaction ,etc .These adverse reactions are mild in severity and self-healing .Since some agents were withdrawn from the market due to severe adverse effects ,we should pay more attention to quinolones .Both internal and abroad literatures were reviewed ,the adverse effects , the high risk factors of the adverse effects and the application in special population were summarized to provide reference for ra-tional clinical drug use .