The function of Vav protein in immune system / 国际儿科学杂志
International Journal of Pediatrics
; (6): 47-50, 2020.
Article
in Zh
| WPRIM
| ID: wpr-799262
Responsible library:
WPRO
ABSTRACT
Vav-family proteins are guanosine nucleotide exchange factors(GEFs)and one of RhoGEFs family numbers.Vav proteins can influence cell signaling transduction, cytoskeleton recombination and adherence migration in special cells by RhoA, RhoG and Rac-1 pathway.There are 80 kinds of RhoGEFs in mammalian cell.Vav proteins play an important role in hematological system, nervous system, cardiovascular system and immune system.So the function of vav protein in immune system was reviewed in this paper.
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WPRIM
Language:
Zh
Journal:
International Journal of Pediatrics
Year:
2020
Type:
Article