Your browser doesn't support javascript.
loading
A Novel Pancreatic Imaging Window for Stabilized Longitudinal In Vivo Observation of Pancreatic Islets in Murine Model
Article in En | WPRIM | ID: wpr-811136
Responsible library: WPRO
ABSTRACT
Longitudinal imaging of murine pancreas is technically challenging due to the mechanical softness of the tissue influenced by peristalsis. Here, we report a novel pancreatic imaging window for long-term stabilized cellular-level observation of the islets in the pancreas in vivo. By spatially separating the pancreas from the bowel movement and physiologic respiration with a metal plate integrated in the imaging window, we successfully tracked the pancreatic islets up to three weeks and visualized the dumbbell-shape transformation from the single islet. This window can be a useful tool for long-term cellular-level visualization of the microstructure in the pancreas.
Full text: 1 Index: WPRIM Language: En Journal: Diabetes & Metabolism Journal Year: 2020 Type: Article
Full text: 1 Index: WPRIM Language: En Journal: Diabetes & Metabolism Journal Year: 2020 Type: Article