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Cycloartane triterpenoid and its glucoside isolated from Cassia occidentalis / 中国天然药物
Article in En | WPRIM | ID: wpr-812036
Responsible library: WPRO
ABSTRACT
In the present study, one new cycloartane triterpenoid, named cycloccidentalic acid C (1) and its glucoside, cycloccidentaliside VI (2) were isolated from the whole plant of Cassia occidentalis. Their structures were elucidated by a combinational analyses of 1D and 2D NMR data and HRMS. Compound 2 showed modest anti-HIV-1 activity with EC value of 1.44 μmol·L and TI (Therapeutic Index) value of 15.59.
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Full text: 1 Index: WPRIM Main subject: Pharmacology / Triterpenes / Plant Extracts / Magnetic Resonance Spectroscopy / Molecular Structure / Cell Survival / Chemistry / Anti-HIV Agents / Inhibitory Concentration 50 / Senna Plant Limits: Humans Language: En Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2017 Type: Article
Full text: 1 Index: WPRIM Main subject: Pharmacology / Triterpenes / Plant Extracts / Magnetic Resonance Spectroscopy / Molecular Structure / Cell Survival / Chemistry / Anti-HIV Agents / Inhibitory Concentration 50 / Senna Plant Limits: Humans Language: En Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2017 Type: Article