Role of local citrate anticoagulation in continuous blood purification to patients at high risk of bleeding in ICU / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1334-1339, 2016.
Article
in Zh
| WPRIM
| ID: wpr-815088
Responsible library:
WPRO
ABSTRACT
To evaluate the safety and efficiency of citrate anticoagulant-based continuous blood purification in patients at high risk of bleeding.
Methods: One hundred and fifty-two patients at high risk of bleeding were divided into local citrate group (group A, n=68) and heparin group (group B, n=84). Clotting function, change of pH, ionized sodium, bicarbonate ion, ionized calcium, activated clotting time (ACT) and complications were monitored before and during treatment.
Results: Compared to the group A, the incidence of clotting in filter and chamber, the degree of bleeding or fresh bleeding were significantly reduced in the group B (P0.05). The pH value, the levels of ionized sodium, bicarbonate ion and ionized calcium during the treatment were maintained in normal range in both group A and group B.
Conclusion: Local citrate-based continuous blood purification can achieve effective anticoagulation and decrease the incidence of bleeding. It is an ideal choice for patients at high risk of bleeding.
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
Reference Values
/
Sodium
/
Bicarbonates
/
Blood
/
Blood Coagulation
/
Blood Coagulation Tests
/
Heparin
/
Calcium
/
Renal Dialysis
Type of study:
Etiology_studies
Limits:
Female
/
Humans
/
Male
Language:
Zh
Journal:
Journal of Central South University(Medical Sciences)
Year:
2016
Type:
Article