Toll-like receptors and non-resolving inflammation-related cancer / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 202-207, 2015.
Article
in Zh
| WPRIM
| ID: wpr-815193
Responsible library:
WPRO
ABSTRACT
Toll-like receptors (TLRs) is a type of pattern recognition receptors (PRRs), which are singular, non-catalytic and highly homologous. TLRs not only play significant roles in natural immunity, but also act as a bridge between innate immunity and adaptive immunity. Recent studies have revealed that TLRs play critical roles in the development of non-resolving inflammation-related cancer,including the formation of tumor microenvironment, invasion and metastasis, immune escape, etc. Further investigation into the mechanisms responsible for the function of TLRs will be of great value in tumor prevention, early diagnosis and therapy.
Full text:
1
Index:
WPRIM
Main subject:
Toll-Like Receptors
/
Tumor Microenvironment
/
Inflammation
/
Neoplasm Invasiveness
/
Neoplasm Metastasis
/
Neoplasms
Type of study:
Screening_studies
Limits:
Humans
Language:
Zh
Journal:
Journal of Central South University(Medical Sciences)
Year:
2015
Type:
Article