Clinical application of total parathyroidectomy combined with autologous transplantationpatient for Chinese patients with secondary hyperparathyroidism:A single arm meta-analysis / 中国实用外科杂志

ABSTRACT

OBJECTIVE: To study the curative effect of total parathyroidectomy combined with autologous transplantationpatient for Chinese patients with secondary hyperparathyroidism. METHODS: Chinese and English databases including Wanfang Science and Technology Periodical Full-text Database,VIP Chinese Science and Technology Periodical Full-text Database(VIP)and CNKI,PubMed were searched by computer. Some relevant studies were collected for Meta analysis. RESULTS: A total of 12 studies including a total of 375 subjects for Meta analysis were identified.After analysis,the postoperative complication rate was P=0.15(95% CI 0.04～0.31),the one-time success rate of surgical operation was P=0.93(95% CI 0.90～0.96),the rate of all-cause mortality was P=0.04(95% CI 0.01～0.07),and the rate of improvement of symptoms was P=0.86(95% CI 0.61～0.99). CONCLUSION: The curative effect of total parathyroidectomy combined with autologous transplantation patient for Chinese patients with secondary hyperparathyroidism is effective. The incidence of postoperative complications is low.