Expression and function of Annexin II in lung cancer tissue

ABSTRACT

OBJECTIVE@#To explore the expression of Annexin II and its relationship with the cell differentiation, proliferation in lung cancer.@*METHODS@#RT-PCR and Western blot assays were used to detect the expression of Annexin II in lung cancer tissues and cell lines.@*RESULTS@#Annexin II was significantly up-regulated in lung cancer tissues, and in lung cancer cell lines, Annexin II had higher mRNA and protein expressions.@*CONCLUSIONS@#Annexin II is up-regulated in lung cancer, suggesting that the Annexin II has a potential value in the human lung cancer.