Effect of acupuncture on inflammatory cytokines expression of spastic cerebral palsy rats
Asian Pacific Journal of Tropical Medicine
; (12): 492-495, 2014.
Article
in En
| WPRIM
| ID: wpr-820664
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To To investigate the effect of acupuncture on the tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), nitric oxide synthase (NOS) content and muscular tension of spasticity cerebral palsy rat model.@*METHODS@#The rats with spastic cerebral palsy were randomly divided into the control group, model group and acupuncture group. After successful modeling, the muscular tension and the content of TNF-α, IL-6, CRP, NOS were measured.@*RESULTS@#The serum TNF-α, IL-6, CRP, NOS content were significantly decreased in the acupuncture group (P<0.05). The low and high shear viscosity of whole blood of the acupuncture group were significantly lower than the control group and the model group (P<0.05). The erythrocyte electrophoresis indexes in the acupuncture group were significantly lower than that in the model group and the control group (P<0.05). Acupuncture significantly reduced the muscular tension of spastic cerebral palsy rat and increased the active extent in the paralytic extremity (P<0.05), but it could not be restored to normal level. Compared with the control group, the difference had significant (P<0.05).@*CONCLUSIONS@#Acupuncture treatment can inhibit the release of inflammatory cells after brain injury, then reduce immune injury, relieve muscle spasms and reduce muscular tension.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Physiology
/
Therapeutics
/
Blood
/
Acupuncture Therapy
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Cerebral Palsy
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Cytokines
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Rats, Wistar
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Hemorheology
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Disease Models, Animal
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Muscle Tonus
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2014
Type:
Article