Investigation and Analysis of Exposure to Antineoplastic Drugs of Medical Staff in Sichuan Province / 中国药房
China Pharmacy
; (12): 1009-1014, 2020.
Article
in Zh
| WPRIM
| ID: wpr-820853
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: To investigation occupational exposure and exposure outcome of antineoplastic in medical staff ,to provide support for their safety in Sichuan Province. METHODS:The respondents included doctors ,nurses,technicians and pharmacists from 11 related departments including tumor department ,hematology department ,PIVAS and pharmacy department in 4 third-level class A hospitals mainly in Sichuan Provincial People ’s Hospital and 6 second-level and below hospitals. Self-designed questionnaires were adopted to investigate general information of medical staff ,cognitive status to occupational exposure hazards , occupational exposure and exposure outcome and protective behaviors and make suggestions of the investigation. RESULTS:A total of 350 questionnaires were sent out and 304 were recovered ,with effective recovery rate of 86.86%. Among 304 investigated pharmacentical staff ,involving 253 female(83.22%),51 male(16.78%),the most of persons aged 20-29 years old (43.42%). The most of persons (66.78%)had a bachelor degree. The largest number of occupation was nurses (55.26%);the pharmacy department had the largest number (21.71%);working hours were mainly 8 h/day(84.21%);working years were the most less than 5 years(39.47%). 121 persons(39.80%)were aware of the potential hazards of occupational exposure to antineoplastic drugs,and 131 persons(43.09%)only knew a little about the Δ 项目基金:国家临床重点专科建设项目;四川省科研院所基本科 exposure hazards ;in PIVAS ,15 persons (71.43%) were 研业务项目(No.2018YSKY0017) *药师,硕士研究生。研究方向:临床药学。E-mail:370951417@ aware of the potential hazards of occupational exposure to qq.com antineoplastic drugs ,accounting the highest proportion among # 通信作者:主任药师,硕士生导师。研究方向:国家药物政策、药 all departments ; the proportion of technicians and other 事管理、医院药学。电话:028-87393436。E-mail:289302309@qq.com medical staff who did not know the occupational exposure 中国药房 2020年第31卷第8期 China Pharmacy 2020Vol. 31 No. 8 ·1009· hazard was the highest ,being 60%;the longer the total working time ,the higher the cognition degree of occupational exposure hazards (P=0.035 8). The most exposed antineoplastic drug was cyclophosphamide 165 persons(54.28%) and pemetrexed disodium 57 persons(18.75%)was the least. The total time of occupational exposure of medical staff in different departments was mainly short-term exposure ,among which the number of exposed persons in hematology department was the most (85.71%). 67 persons(22.04%)reported that they had physical discomfort after excluding the influence of other physical diseases ,mainly the increase of alopecia (73.13%);the propertion of medical staff who had physical discomfort in hematology department was the most(50.00%);the number of nurses who had physical discomfort (31.55%)was the most. 155 persons(50.99%)could not understand the antineoplastic drug protection measures ,41 persons (13.49%) had received relevant training ,108 persons (35.53%)understood the occupational protection of antineoplastic drugs. The highest level of awareness of protective measures was found among the medical staff in PIVAS ,and only 14.29% of the staff did not understand the protective measures. In term of occupation,the proportion of nurses who had received relevant training was the highest (19.05%). CONCLUSIONS :Medical staffs have a low level of knowledge about occupational exposure hazards and self-protection measures of antineoplastic drugs. The government should strengthen the construction of occupational protection regulations and standards for medical staff ;hospitals should strengthen internal management and attach great importance to the management of occupational protection in hospitals ; medical staff should increase awareness ,skills and reduce the risk of occupational exposure.
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WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2020
Type:
Article