Biocatalysis of formaldehyde to L-xylose / 生物工程学报
Chinese Journal of Biotechnology
; (12): 942-948, 2020.
Article
in Zh
| WPRIM
| ID: wpr-826882
Responsible library:
WPRO
ABSTRACT
It is of great significance to use biosynthesis to transform the inorganic substance formaldehyde into organic sugars. Most important in this process was to find a suitable catalyst combination to achieve the dimerization of formaldehyde. In a recent report, an engineered glycolaldehyde synthase was reported to catalyze this reaction. It could be combined with engineered D-fructose-6-phosphate aldolase, a "one-pot enzyme" method, to synthesize L-xylose using formaldehyde and the conversion rate could reach up to 64%. This process also provides a reference for the synthesis of other sugars. With the increasing consumption of non-renewable resources, it was of great significance to convert formaldehyde into sugar by biosynthesis.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Xylose
/
Chemistry
/
Biocatalysis
/
Formaldehyde
/
Fructose-Bisphosphate Aldolase
/
Metabolism
Language:
Zh
Journal:
Chinese Journal of Biotechnology
Year:
2020
Type:
Article