New meroterpenoids and C-methylated flavonoid isolated from Baeckea frutescens / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 379-384, 2020.
Article
in En
| WPRIM
| ID: wpr-827232
Responsible library:
WPRO
ABSTRACT
Phytochemical investigation of the aerial parts of Baeckea frutescens resulted in the isolation of three new mono- or sesquiterpene-based meroterpenoids, frutescones S-U (1-3), and one pair of new (±)-5,7-dihydroxy-8-isobutyryl-6-methyldihydroflavonol (4). Their structures and absolute configurations were established by HR-ESI-MS, 1D and 2D NMR, and quantum chemical ECD calculation. Compound 1 exhibited inhibitory effect on NO production in LPS-activated RAW 264.7 macrophages with an IC value being 0.81 μmol·L.
Full text:
1
Index:
WPRIM
Language:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2020
Type:
Article