Detection of Pseudorabies Virus Antibodies in Human Encephalitis Cases / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 444-447, 2020.
Article
in En
| WPRIM
| ID: wpr-828995
Responsible library:
WPRO
ABSTRACT
Pseudorabies virus (PRV), a veterinary pathogen that infects domestic animals as well as wild animals such as wild boar and feral swine, was recently reported to infect human and led to endophthalmitis and encephalitis. A retrospective seroepidemiologic survey was conducted using 1,335 serum samples collected from patients with encephalitis and ELISA positive rates were 12.16%, 14.25%, and 6.52% in 2012, 2013, and 2017, respectively. The virus neutralizing antibody titers of positive samples correlated well with ELISA results. The pseudorabies virus antibody positive rate of patients with encephalitis were higher than that of healthy people in 2017. The above results suggest that some undefined human encephalitis cases may be caused by PRV infection.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pseudorabies
/
Virology
/
Blood
/
Enzyme-Linked Immunosorbent Assay
/
Seroepidemiologic Studies
/
China
/
Prevalence
/
Retrospective Studies
/
Herpesvirus 1, Suid
/
Encephalitis
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
Limits:
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Biomedical and Environmental Sciences
Year:
2020
Type:
Article