Five new gingerol compounds from Zingiberis Rhizoma / 药学学报
Acta Pharmaceutica Sinica
; (12): 2421-2427, 2020.
Article
in Zh
| WPRIM
| ID: wpr-829378
Responsible library:
WPRO
ABSTRACT
We separated and purified five chemical constituents of dried ginger by Diaion HP-20, Sephadex LH-20, silica gel and semi-preparative high performance liquid chromatography. Five gingerols were identified by physicochemical properties and MS and NMR spectroscopy techniques: 4-(2-butyl-6-methyl-4H-pyran-4-yl)-2-methoxyphenol (1), 4-(2-hexyl-6-methyl-4H-pyran-4-yl)-2-methoxyphenol (2), 1-(4-hydroxy-3-methoxyphenyl)tridecane-3,5-diol (3), [10]-gingerdiol (4) and 1-[1-(4-hydroxy-3-methoxy phenyl)-3-oxodecan-5-yl]pyrrolidin-2-one (5a, 5b). Compounds 1-3, 5a, 5b are new compounds.
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Index:
WPRIM
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2020
Type:
Article