Extraction optimization for Yinsangju solid beverage by orthogonal design and Box-Behnken design-response surface methodology / 国际药学研究杂志
Journal of International Pharmaceutical Research
; (6): 761-767, 2016.
Article
in Zh
| WPRIM
| ID: wpr-845531
Responsible library:
WPRO
ABSTRACT
Objective: To optimize extraction process of Yinsangju solid beverage(YSJ). Methods: The extraction of YSJ was preliminarie optimized through the orthogonal design,and then further optimized by Box-Behnken design-response surface with the overall desirability (OD) of chlorogenic acid and polysaccharide content and yield of extract as evaluation indexes. Results: The optimum extraction of orthogonal design was as follow: 10 times the amount of water,soaked 0.5 h,extracted 2 times,each time 1.5 h. The optimum extraction of Box-Behnken design was 10.82 times the amount of water,soaked 0.51 h,extracted 2 times,each time 1.77 h. Conclusion: The test results show that the Box-Behnken response surface method optimization of extraction process parameters is more precise and more detailed and predictability is good, and the product quality is improved.
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Index:
WPRIM
Language:
Zh
Journal:
Journal of International Pharmaceutical Research
Year:
2016
Type:
Article