Effect of temperature and time on rheological properties of Daphnes Giraldii Cortex post-crosslinking gel plaster / 中草药

ABSTRACT

Objective: To provide scientific basis for the temperature condition of Daphnes Giraldii Cortex (DGC) post-cross-linked gel plaster during storage and transportation. Methods: Taking linear viscoelastic region, modulus, yield stress, phase angle, composite viscosity and creep compliance as evaluation indexes, amplitude scanning, frequency scanning, temperature scanning and creep testing were carried out on the cross-linked gel plaster matrix after DGC by an advanced rotary rheometer, and relevant data of elastic modulus, viscosity modulus, phase angle, composite viscosity, creep compliance and yield stress of the samples which were stored at room temperature, -20 ℃ and -50 ℃ for 1, 3, 8, and 13 d were respectively obtained. Results: All samples of DGC post-crosslinking gel plaster showed elastic characteristics and stable state. After storage under different conditions, the state is still stable and the dispersibility is better. The peel strength of samples stored for 8 d and 13 d was decreased. The retention of samples stored at -50 ℃ for 13 d was decreased. Conclusion: DGC plaster containing post-crosslinked gel matrix had stable state, good dispersibility, initial adhesion, peel strength and shape retention when samples were stored below 0 ℃ for 3 d.