Research approach on quality control of Astragalus polysaccharides based on polysaccharide receptor theory / 中草药

ABSTRACT

Astragali Radix is a commonly used staple Chinese herbal medicine with high medicinal and edible value. Its chemical composition mainly contains saponins, flavonoids, polysaccharides, and amino acids. Among them, Astragalus polysaccharides (APS), as the main active component of Astragali Radix, failed to be used as a quality control index to evaluate germplasm resources due to its non-specificity and weaker controllability. The proposal and application of polysaccharide receptor theory provides a new way to solve the international problem of quality control of polysaccharide drugs. In this paper, several related research literatures on the quality control of polysaccharides from Astragali Radix and polysaccharide receptor theory in recent years were reviewed, and the research ideas of quality control of Astragalus oligosaccharide active center were proposed.