Research progress on biosynthetic pathways and related enzymes of iridoid glycosides / 中草药

ABSTRACT

Iridoids glycosides are a class of compounds which have pharmacological functions of anti-inflammatory, antitumor, hepato-protection, cardio-protection, etc. This review summarizes the biosynthetic pathway, related enzymes (GPPS, GES, G10, G10H, 10-HGO, IS, 7-DLS, 7-DLGT, 7-DLH, LAMT, and SLS) and the application of functional genes in iridoids glycosides, in hopes of regulating the production of metabolites and providing the valuable reference for discovering new drugs.