Research progress in antidepressive active ingredients and pharmacological effects of Angelicae Sinensis Radix / 中草药

ABSTRACT

Through literature analysis, this paper summarizes the application of Angelicae Sinensis Radix in depression. The organic acids, phthalides, and polyacetylenes of Angeliae Sinensis Radix have the effect of antidepression, neuroprotective and monoamine reuptake inhibition. This paper reviewed that Angelicae Sinensis Radix improved the possible mechanisms of depression including injury of nerve, oxidative stress, and neurotransmitter system disorders, which will provide scientific basis for clinical treatment of depression.