Systemic Amyloid Protein a Amyloidosis Involving the Heart in a Patient with Rheumatoid Arthritis / 대한내과학회지
Korean Journal of Medicine
; : 739-743, 2014.
Article
in Ko
| WPRIM
| ID: wpr-85491
Responsible library:
WPRO
ABSTRACT
Amyloidosis can be identified by the deposition of amyloid fibrils in biopsy specimens from multiple organs, including the heart, kidney, skin, and bowel. Systemic amyloid protein A amyloidosis (AA amyloidosis) is commonly associated with chronic inflammatory diseases or chronic infectious conditions. Cardiac involvement in AA amyloidosis is found in < 1% of reported cases. Here, we report a case of cardiac AA amyloidosis confirmed by heart biopsy in a 54-year-old-female with a medical history of rheumatoid arthritis and stage 4 chronic kidney disease due to renal amyloidosis. She had suffered from progressive aggravation of dyspnea for 2 years. Infiltrative disease involving the heart was suspected by echocardiography, and the patient was diagnosed with AA amyloidosis involving the heart by cardiac biopsy. This is a rare case of cardiac involvement in a patient with systemic AA amyloidosis associated with rheumatoid arthritis.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Arthritis, Rheumatoid
/
Rheumatic Fever
/
Skin
/
Staphylococcal Protein A
/
Biopsy
/
Echocardiography
/
Dyspnea
/
Renal Insufficiency, Chronic
/
Heart
/
Heart Failure
Type of study:
Prognostic_studies
Limits:
Humans
Language:
Ko
Journal:
Korean Journal of Medicine
Year:
2014
Type:
Article