Asymmetry of Auditory Event-Related Potential P300 in Patients with Schizophrenia / 신경정신의학

ABSTRACT

OBJECTIVE: The present study was designed to investigate whether asymmetry of auditory event-related potential P300 was shown in patients with schizophrenia or not. METHOD: The subjects were composed of patients(N=20) with schizophrenia by DSM-IV and normal controls(N=20). The auditory event related potential P300 was measured by "oddball paradigm". P300 component was determined by classic method at 5 electrodes(Fz, Cz, Pz, T3, T4). RESULTS: P300 amplitudes of patients were smaller than those of controls across all electrodes. Asymmetry of auditory event-related potential P300 was not shown between patients with schizophrenia and normal controls. CONCLUSION: It is implicated that auditory event-related potential P300 and its information processing should not be elicited asymmetrically in schizophrenia.