Application of supercritical fluid precipitation technology for preparation of poorly water-soluble drugs / 中国药学杂志

ABSTRACT

To improve the dissolution and bioavailability of poorly water-soluble drugs have been being emphasis and difficulty in pharmaceutical research. Supercritical fluid precipitation(SFP) technology has an extensive prospect in new drug delivery systems of the poorly water-soluble drugs base on its advantages, such as green, friendliness to the environment and it is possible to achieve industrial-scale production. In this paper, related literatures were retrieved to summarize the application of SFP for preparation of poorly water-soluble drugs in recent years.