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Research progress in nanogel carrier systems / 中国药学杂志
Chinese Pharmaceutical Journal ; (24): 177-182, 2016.
Article in Chinese | WPRIM | ID: wpr-859217
Responsible library: WPRO
ABSTRACT
Nanogels combine the advantages of hydrogels and nanoparticles, such as small particle size, prolonged blood circulation time, biocompatibility, biodegradation and high drug loading. Common carrier materials is used for the preparation of nanogels include polyacrylic acid, polyacrylamide, pluronic, polysaccharide and their derivates. They can be cross-linked based on amine reaction, "click" chemistry, photo-induced cross-linking, physical cross-linking or heterogeneous polymerization of monomers to form nanogel carrier systems. Nanogels, as ideal and novel drug delivery systems, have great promise in the delivery of chemotherapeutic drugs, proteins and genes. The carrier materials, preparation methods and applications of nanogels were reviewed based on relevant articles published in recent years.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmaceutical Journal Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmaceutical Journal Year: 2016 Type: Article