Diagnostic value of DWI with high b value in diagnosis of benign and malignant breast lesions: Meta-analysis / 中国医学影像技术

ABSTRACT

Objective: To explore the diagnostic value of DWI with high b value for benign and malignant breast lesions. Methods: PubMed, Embase, Cochrane Library, Wanfang Med Online, CNKI and VIP databases were searched from the establishment of database to October 2019. Chinese and English literature about the observation of benign and malignant breast lesions with high b value DWI were included, and the quality evaluation and data extraction of the final included articles were carried out. Meta-Disc 1. 4 software was used for statistical analysis to test the heterogeneity of the studies, the forest map and the summary receiver operating characteristic (SROC) curve were drawn, and area under the curve (AUC) was calculated. Stata 15.0 software was used to test publication bias. Results: Totally 18 eligible articles were included for meta-analysis, the pooled sensitivity of high b value DWI in evaluating benign and malignant breast lesions was 0.88, the pooled specificity was 0.84, the ratio of the pooled diagnostic ratio was 51.97, and the AUC of SROC was 0.94, Q index was 0.88. Conclusion: The sensitivity and specificity of DWI with high b value in diagnosis of benign and malignant breast lesions were both high, which could be used in differential diagnosis of benign and malignant breast lesions.