Ultrasonography in evaluation on abnormal motion of diaphragms in patients with chronic obstructive pulmonary disease / 中国医学影像技术

ABSTRACT

Objective: To explore the value of ultrasonography in evaluation on abnormal motion of the diaphragms in patients with chronic obstructive pulmonary disease (COPD). Methods: Totally 64 patients with COPD in acute exacerbation were enrolled and divided into C group (n=34) and D group (n=30) according to 2017GOLD guidelines. All patients underwent ultrasonography. The thickness of diaphragm, the range of motion of diaphragm and the angle of conjunction, as well as diaphragmatic thickening fraction (DTF) and the degree of diaphragm (DD) were measured and calculated. Results: DTF and contraction speed of diaphragm in C group were significantly higher than those in D group (both P0.05). DTF was positively correlated with the ratio between forced the first second of expiratory volume and forced vital capacity (FEV1/FVC, r=0.26, P=0.04), while DD (r=0.35, P<0.01) and contraction speed (r=0.43, P<0.01)were positively correlated with forced vital capacity (FVC). The differential diagnosis performance of DTF for C group and D group COPD was relatively good (AUC=0.78), taken diagnostic threshold of 30.22%, the sensitivity and specificity was 70.60% and 83.30%, respectively. Conclusion: Ultrasound can be used to evaluate diaphragmatic dysfunction in patients with COPD and guide the stable rehabilitation treatment.