18F-FDG PET/CT manifestations of Langerhans cell histiocytosis in adult spine / 中国医学影像技术

ABSTRACT

Objective To observe 18F-FDG PET/CT manifestations of Langerhans cell histiocytosis (LCH) of the adult spine. Methods 18F-FDG PET/CT imaging features of 9 adult patients with LCH of spine confirmed by pathology were retrospectively analyzed. The lesions number, location, density, margin and the maximum standardized uptake (SUVmax) were observed. Results Among 9 cases (18 lesions of spine), single lesion was found in 6 patients, while multiple lesions were found in 3 patients. Sixteen lesions displayed different degrees of osteolytic bone destruction, with sharp margins and were filled with soft tissue, 7 lesions showed rim osteosclerosis, while 3 lesions invaded canalis vertebralis. Another 2 lesions were found as shape shadow of slightly high density and no density abnormity, respectively. High 18F-FDG uptake was found in all 18 lesions, the mean SUVmax was 9.07±4.99. Conclusion 18F-FDG PET/CT manifestations of LCH of adult spine have some characteristics, which are helpful to the diagnosis of this disease.