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Progress in clinicopathological features of Ewing's sarcoma and Ewing-like sarcoma / 中国肿瘤临床
Article in Chinese | WPRIM | ID: wpr-861659
Responsible library: WPRO
ABSTRACT
Ewing's sarcoma and Ewing-like sarcoma are highly invasive sarcomas predominantly characterized by the presence of small round cells. Although certain morphological and immunophenotypical characteristics are similar between the two sarcomas, there are obvious differences in the disease sites, clinical manifestations, prognoses, and treatment responses. Additionally, Ewing-like sarcomas lack the typical molecular characteristics of Ewing's sarcoma. A growing body of evidence shows that Ewing-like sarcomas constitute a different disease type with unique characteristics, and are not just a subtype of Ewing's sarcoma. The discovery of novel molecular genetic tests has significantly aided the reevaluation of the classification of small round cell tumors. This article aims to review the recent progress in the research on Ewing's sarcoma and the major subclasses of Ewing-like sarcoma characterized thus far CIC rearrangement sarcoma, BCOR rearrangement sarcoma, non-ETS family gene rearrangement sarcoma, and undifferentiated small round cell sarcoma.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Clinical Oncology Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Clinical Oncology Year: 2021 Type: Article