Advances in Research on Role and Mechanism of Polyphylla Saponin in Digestive System Tumors / 胃肠病学

ABSTRACT

Polyphylla saponin is the major effective ingredient of polyphylla. Pharmacology research showed that polyphylla saponin could effectively inhibit the occurrence and development of malignant tumor of digestive system via inhibiting tumor cell proliferation, promoting tumor cell apoptosis, inhibiting tumor neovascularization, inhibiting tumor cell migration, regulating tumor cell immune function, regulating tumor cell resistance to chemotherapeutic drugs. This article reviewed the role and mechanism of polyphylla saponin in digestive system tumors.