The research progress on the effect of obstructive sleep apnea hypopnea on cognitive impairment in patients with cerebral microvascular disease / 中国医师杂志

ABSTRACT

Cerebral small vessel disease(CSVD) refers to the syndrome of clinical, cognitive, imaging and pathological manifestations caused by intracranial small vascular lesions (intracranial arterioles, arterioles, capillaries and venules, etc.). The course of the disease is hidden, and the clinical is often lack of specificity, of which cognitive impairment is the most common. In recent years, it has been found that obstructive sleep apnea hypopnea syndrome(OSAHS) is one of the high risk factors of CSVD, which can aggravate the progress of cognitive impairment. This article will review the mechanism of the effect of OSAHS on cognitive impairment in CSVD.