Analysis of whole-body bone scintigraphy and SPECT/CT imaging in osteoid osteoma / 中华核医学与分子影像杂志

ABSTRACT

Objective To analyze features of osteoid osteoma on whole-body bone scan (WBS) and SPECT/CT imaging.Methods From January 2010 to December 2018,70 patients (50 males,20 females,age:4-66 years) with osteoid osteoma confirmed by pathology were enrolled from the Affiliated Hospital of Southwest Medical University.All patients underwent WBS and SPECT/CT imaging and imaging features were retrospectively analyzed.Results A total of 70 lesions were found by WBS combined with SPECT/CT imaging,and 26 lesions (37.1％,26/70) were found in the femur and 25 lesions (35.7％,25/70) in the tibia.The radioactive ratio of target lesion to non-target lesion (T/NT) was 3.7±1.2 in 56 patients who underwent three-phase bone imaging.WBS showed that 48 lesions (68.6％,48/70) were round (or nearly round),21 lesions (30％,21/70) were spindle-shaped,and 1 lesion (1.4％,1/70) was irregular-shaped,while SPECT/CT imaging showed that 69 lesions (98.6％,69/70) were round (or round) and 1 lesion (1.4％,1/70) was irregular-shaped.The "double-density sign" was found in 48 lesions (68.6％,48/70) by WBS and in 59 lesions (84.3％,59/70) by SPECT/CT imaging.SPECT/CT imaging detected nidus in 59 lesions (84.3％,59/70) and calcification or ossification ("target sign") in 27 lesions (38.6％,27/70).Conclusion The typical features of osteoid osteoma on WBS and SPECT/CT imaging include "double density sign",nidus and "target sign",which contribute to the diagnosis of osteoid osteoma.