The correlation of neutrophil-lymphocyte ratio and platelet parameters with the prognosis of elderly patients with cerebral hemorrhage / 中华老年医学杂志

ABSTRACT

Objective:To investigate the correlation of peripheral blood neutrophil-lymphocyte ratio(NLR)and platelet parameters with the prognosis of elderly patients with cerebral hemorrhage.Methods:Clinical data of 80 patients with cerebral hemorrhage admitted to the neurosurgery department of our hospital from January 2017 to July 2019 were retrospectively analyzed.Based on modified Rankin scale scores, they were classified into the good prognosis group(n=49, with modified Rankin scale scores <3 points)and the poor prognosis group(n=31, with modified Rankin scale scores between 3-6 points). General demographic data and results on laboratory indexes including platelet(PLT), platelet distribution width(PDW), mean platelet volume(MPV), absolute lymphocyte count(ALC)and absolute neutrophil count(ANC)were compared between the two groups.Logistic regression analysis was performed to examine the effects of platelet parameters and NLR on the prognosis of elderly patients with cerebral hemorrhage.Results:NLR, PDW and MPV were higher and PLT was lower in the poor prognosis group than in the good prognosis group[(8.89±1.95) vs. (3.13±0.21), (16.75±4.32) % vs.(12.89±2.71) %, (14.82±3.52) % vs. (10.78±1.62) %, (0.37±0.20) % vs.(0.62±0.33) %, t=20.564, 4.918, 6.969 and 4.918, all P<0.001)]. Logistic regression analysis showed that increased levels of NLR, PDW and MPV and decreased levels of PLT were influencing factors for poor prognosis in elderly patients with cerebral hemorrhage( OR=2.759, 2.606, 1.756 and 0.095, all P<0.001). Conclusions:NLR, PDW, MPV and PLT are closely correlated with the prognosis of elderly patients with cerebral hemorrhage and may be used as indexes for prognosis evaluation in these patients.