A study on the clinicopathological features and prognosis of colorectal cancer patients / 中华普通外科杂志

ABSTRACT

Objective:To investigate prognostic factor in colorectal cancer (CRC).Methods:The clinicopathologic characteristics and progression free survival (PFS) of 181 CRC patients treated from Mar 2015 to Dec 2017 was collected for analysis. Univariate and multivariate analysis were performed to screen for prognostic factors affecting prognosis.Results:Univariate analysis found that age(χ 2=12.192, P=0.002), AJCC staging(χ 2=17.038, P=0.001), surgical approach(χ 2=6.105, P=0.047), postoperative carcinoembryonic antigen ( χ 2=10.081, P=0.001 ) and perioperative adverse events (χ 2=6.736, P=0.009)were significantly associated with prognosis. Multivariate analysis found that AJCC staging(Wald =8.104, P=0.044) and perioperative adverse events(Wald=7.656, P=0.006) were independent risk factors for prognosis. Conclusions:AJCC staging and perioperative adverse events can be used as independent risk factors for predicting prognosis in CRC patients.