Acute Myeloid Leukemia with t(8;21)(q22;q22) (AML1/ETO) in a Patient with Marked Hypocellularity and Low Blasts Count / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 85-90, 2007.
Article
in English
| WPRIM
| ID: wpr-8716
ABSTRACT
According to the World Health Organization (WHO) classification system, cases with t(8;21)(q22;q22) should be diagnosed as acute myeloid leukemia (AML) even with a blast count of less than 20 percent in blood or bone marrow. It is an uncommon manifestation, moreover hypocellularity is rarely observed in this subtype of leukemia. Here, we report a case of t(8;21) in a patient with marked hypocellularity of less than 5 percent and a blast count of less than 20 percent. This patient responded relatively well to chemotherapy. An allogeneic bone marrow transplantation was performed with good engraftment . This case suggests that hypocellular AML with a t(8;21) has as good a prognosis as hypercellular AML with t(8;21).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
World Health Organization
/
Bone Marrow
/
Leukemia, Myeloid, Acute
/
Leukemia
/
Bone Marrow Transplantation
/
Classification
/
Drug Therapy
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Yeungnam University Journal of Medicine
Year:
2007
Type:
Article
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