Current clinical situation and challenge for liquid chromatography-tandem mass spectrometry in quantitative detection / 中华检验医学杂志

ABSTRACT

The performance of high sensitivity, specificity and throughput makes liquid chromatography-tandem mass spectrometry (LC-MS/MS) quickly developed and well applicated in clinical laboratories, such as quantitative detection of steroids, vitamins and metabolic small molecules, monitoring drug concertrations as well as the establishing reference methods or verifying reference materials. However, there were still some challenges for the widespread clinical application of LC-MS/MS.