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Assessment on the Effects of Hepatitis B Prevention and Control Measures in Western China: A Comparison of Three Population-based Serosurveys / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 735-744, 2020.
Article in English | WPRIM | ID: wpr-878291
ABSTRACT
Objective@#Despite the remarkable progress in efforts to control disease spread, the nationwide elimination of hepatitis B in China is still hindered by the persistently high rate of hepatitis B virus (HBV) infection in Western China. This study aimed to evaluate the strategy of hepatitis B prevention and control in Western China and identify potential areas and strategies for improvement.@*Methods@#Susceptible population vaccination, health education, professional training of doctors, and other prevention and control measures have been implemented in Wuwei city since 2010. Data were obtained from three representative cross-sectional serosurveys conducted in 2010, 2013, and 2015. The serum samples were subjected to enzyme-linked immunosorbent assays to detect the following seromarkers HBV surface antigen (HBsAg), antibody against hepatitis B surface antigen (anti-HBs), and antibody against hepatitis B core antigen (anti-HBc). Estimates of variance were determined using Taylor series linearization methods.@*Results@#The three serosurveys revealed decreases in the prevalence of HBsAg (7.19% in 2010 @*Conclusion@#Although vaccine-based prevention and control measures reduced the rate of HBV infection in Wuwei City over time, the hepatitis B infection rate in children younger than 10 years was still higher than the national average level. Therefore, the prevention and control of mother-to-child transmission and the management of the infected should be the focus of future prevention and control work.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Seroepidemiologic Studies / China / Communicable Disease Control / Hepatitis B virus / Prevalence / Cross-Sectional Studies / Hepatitis B Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Seroepidemiologic Studies / China / Communicable Disease Control / Hepatitis B virus / Prevalence / Cross-Sectional Studies / Hepatitis B Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2020 Type: Article