Main chemical constituents in aerial parts of Glycyrrhiza uralensis by UPLC-Q-Exactive Orbitrap-MS / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1449-1459, 2021.
Article
in Zh
| WPRIM
| ID: wpr-879050
Responsible library:
WPRO
ABSTRACT
Chemical constituents from aerial parts of Glycyrrhiza uralensis were analyzed and identified using ultra-high performance liquid chromatography coupled with hybrid quadrupole-orbitrap mass spectrometry(UPLC-Q-Exactive Orbitrap-MS). The chromatographic column of Waters Acquity UPLC BEH-C_(18)(2.1 mm×100 mm, 1.7 μm) was adopted, with acetonitrile-water(0.5% formic acid) as mobile phase at a flow rate of 0.2 mL·min~(-1). Data was collected in positive and negative modes of electrospray ionization(ESI). A total of 55 compounds, including 42 flavonoids, 9 stilbenes, 2 coumarins, 1 lignin and 1 phenolic acid, which were characterized in the aerial parts of G. uralensis based on accurate molecular mass information of molecular and product ions provided by UPLC-Q-Exactive Orbitrap-MS based on comparison with standard substances and references. It is an effective and accurate method to provide chemical information of constituents in aerial parts of G. uralensis, and can provide a reference for further study on pharmacodynamic material basis and resources development and utilization.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Mass Spectrometry
/
Drugs, Chinese Herbal
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Chromatography, High Pressure Liquid
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Glycyrrhiza uralensis
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Plant Components, Aerial
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2021
Type:
Article